Boron Neutron Capture Therapy

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Positron Emission TomographyThe patient, a 73-year-old male, was diagnosed as having maxillary sinus cancer on the right side of his face four years ago. After surgical removal of the tumor, he underwent radiation and chemotherapy, followed by BNCT. When a tumor mass returned in the area that had been treated, the patient underwent an FBPA PET test. A high accumulation of FBPA was confirmed in the recurrent tumor mass. The level of accumulation was about five times higher than in the surrounding healthy tissue, and he was diagnosed with a recurrence of the tumor and determined to be a candidate for BNCT. (This patient was referred by Dr. Itsurou Kato at Osaka University.) The patient, a 63-year-old male, was diagnosed as having lung cancer one year ago and had the tumor surgically removed. Later, the patient developed a metastatic brain tumor in his left frontal lobe. After gamma knife treatment, imaging revealed that a ring-shaped tumor remained. An FBPA PET test indicated that accumulation in the tumor was only about two times that of the surrounding healthy tissue, prompting a determination that the patient was not a candidate for BNCT. (This patient was referred by Shin’ichi Miyatake at Osaka Medical College.)A case showing high FBPA accumulation in a head and neck tumorA case with non-accumulation in a suspected brain tumorFBPA PETFBPA PET8

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